Mounjaro® (tirzepatide) is a single medication designed to activate two natural hormone receptors in the body: GIP and GLP-1. Its structure is based on the body’s natural GIP hormone, allowing it to act on both GIP and GLP-1 receptors found on the surface of cells. Its activity at the GIP receptor is similar to natural GIP, while its activity at the GLP-1 receptor is lower than that of the body’s natural GLP-1 hormone. Mounjaro has an average half-life of approximately five days, which allows it to be taken once weekly as prescribed.

Before beginning treatment, please read the Instructions for Use and the Patient Information Leaflet supplied with your medication.

• Mounjaro is taken once a week. It can be used at any time of day, with or without food.
  
• Inject Mounjaro under the skin of your abdomen or thigh. If using the back of your upper arm, another person should give the injection.
  
• Choose a different injection site each week. If you also use insulin, inject it at a different site from your Mounjaro injection.
  
• Like all medicines, Mounjaro can cause side effects. The most commonly reported include nausea, diarrhoea, vomiting and constipation. Speak to your pharmacist or healthcare professional if you are concerned about any symptoms.
  
• If you miss a dose, take it as soon as possible within four days. If more than four days have passed, skip the missed dose and take your next dose on your usual scheduled day. Never take two doses less than three days apart.
  
• You may change your usual injection day if necessary, provided there are at least three days between doses.